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DSIP is not approved by the FDA or any other major health authority

Reported side effects are minimalprimarily mild nasal irritation with intranasal administration

In this review, we discuss the pipeline of obesity pharmacotherapies with focus on entero-pancreatic hormone-based molecules, and we evaluate the data from early and late phase clinical trials on their safety and efficacy on WL in people with and without T2D

As an important channel of essential oxygen and energy sources for the brain, cerebral microvessels are an important component of the bloodbrain barrier (BBB), and its disruption is an early pathophysiological mechanism in neurodegenerative diseases (20)